Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice
Abstract
The uterine fibrosis contributes to gestational outcomes. Collagen deposition in the uterus is related to uterine aging. Senolytic therapies are an option for reducing health complications related to aging. We investigated effects of aging and the senolytic drug combination of dasatinib plus quercetin (D+Q) on uterine fibrosis. Forty mice, 20 young females (03-months) and 20 old females (18-months), were analyzed. Young (Y) and old (O) animals...
Paper Details
Title
Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice
Published Date
Jan 18, 2020
Journal
Volume
12
Issue
3
Pages
2711 - 2722
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