Postbronchodilator lung function improvements with benralizumab for patients with severe asthma

Airway remodeling and loss of lung function are prominent features of asthma.1 Activated eosinophils release an array of inflammatory cytokines and lipid mediators that play a role in airway remodeling.2 Imaging studies using quantitative computed tomography have demonstrated correlations between parameters of airway remodeling and postbronchodilator forced expiratory volume in 1 second (FEV1) as well as changes over time.3, 4 Therefore, we...