Genome‐wide identification of Listeria monocytogenes CodY‐binding sites

CodY is a global transcriptional regulator that controls, directly or indirectly, the expression of dozens of genes and operons in Listeria monocytogenes . We used in vitro DNA affinity purification combined with massively parallel sequencing (IDAP‐Seq) to identify genome‐wide L. monocytogenes chromosomal DNA regions that CodY binds in vitro. The total number of CodY‐binding regions exceeded 2,000, but they varied significantly in their...