JAK-ing into M1/M2 Polarization SteErs Salmonella-Containing Macrophages Away from Immune Attack to Promote Bacterial Persistence
Abstract
Despite decades of study, the molecular basis for granuloma formation and restriction of chronic pathogens remains murky. Three articles reveal how Salmonella rewires macrophage polarization (Panagi et al. and Gibbs et al.) to shift the balance between M1 and M2 granuloma macrophages and resist TNF-mediated clearance (Pham et...
Paper Details
Title
JAK-ing into M1/M2 Polarization SteErs Salmonella-Containing Macrophages Away from Immune Attack to Promote Bacterial Persistence
Published Date
Jan 1, 2020
Journal
Volume
27
Issue
1
Pages
3 - 5
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Notes
History