Enabling a Single Deep Learning Model for Accurate Gland Instance Segmentation: A Shape-Aware Adversarial Learning Framework

Segmenting gland instances in histology images is highly challenging as it requires not only detecting glands from a complex background but also separating each individual gland instance with accurate boundary detection. However, due to the boundary uncertainty problem in manual annotations, pixel-to-pixel matching based loss functions are too restrictive for simultaneous gland detection and boundary detection. State-of-the-art approaches...