Insight into the Formation of Glimepiride Nanocrystals by Wet Media Milling
Abstract
Nanocrystal formation for the dissolution enhancement of glimepiride was attempted by wet media milling. Different stabilizers were tested and the obtained nanosuspensions were solidified by spray drying in presence of mannitol, and characterized regarding their redispersibility by dynamic light scattering, physicochemical properties by differential scanning calorimetry (DSC), FT-IR spectroscopy, powder X-ray diffraction (PXRD), and scanning...
Paper Details
Title
Insight into the Formation of Glimepiride Nanocrystals by Wet Media Milling
Published Date
Jan 9, 2020
Journal
Volume
12
Issue
1
Pages
53 - 53
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