Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis
Volume: 11, Issue: 1
Published: Jan 16, 2020
Abstract
Excessive mitochondrial fission acts as a pro-proliferative marker in some cancers and organ fibrosis; its potential role in renal fibroblast activation and fibrogenesis has never been investigated. Here, we showed more pronounced fragmented mitochondria in fibrotic than in non-fibrotic renal fibroblast in humans and mice. In a mouse model of obstructive nephropathy, phosphorylation of Drp1 at serine 616 (p-Drp1S616) and acetylation of...
Paper Details
Title
Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis
Published Date
Jan 16, 2020
Volume
11
Issue
1
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History