The effect of fluid shear stress on fibroblasts and stem cells on plane and groove topographies

Volume: 14, Issue: 1, Pages: 12 - 23
Published: Jan 1, 2020
Abstract
In this study, we aimed to study the effect of fluid shear stress on fibroblasts and BMSCs on plane and groove topographies. The results showed that 0.6-Hz stress had the greatest influence on the alignment, polarity, migration and adhesion of fibroblasts on plane by increasing the expression of reoriented actin and vinculin; whereas 1.0-Hz stress promoted differentiation of fibroblasts into myofibroblasts by increasing Col-I and α-SMA...
Paper Details
Title
The effect of fluid shear stress on fibroblasts and stem cells on plane and groove topographies
Published Date
Jan 1, 2020
Volume
14
Issue
1
Pages
12 - 23
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