Original paper
Exogenous 8‐hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1‐NADPH oxidase signaling
Volume: 35, Issue: 6, Pages: 1078 - 1087
Published: Jan 23, 2020
Abstract
Background and Aim Exogenous 8‐hydroxydeoxyguanosine (8‐OHdG) was suggested as an inhibitor of Rac1 and NADPH oxidase (NOX). The aim of this study was to evaluate the effects of the exogenous 8‐OHdG on hepatic fibrogenesis in vitro and in vivo model of liver fibrosis. Methods Adult Sprague–Dawley rats were allocated to sham‐operated rats ( n = 7), rats that underwent bile duct ligation (BDL) (n = 6), and BDL rats treated with 8‐OHdG (60...
Paper Details
Title
Exogenous 8‐hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1‐NADPH oxidase signaling
Published Date
Jan 23, 2020
Volume
35
Issue
6
Pages
1078 - 1087
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