White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease

Volume: 94, Issue: 9, Pages: e950 - e960
Published: Dec 30, 2019
Abstract
Recent studies suggest that white matter hyperintensities (WMH) on MRI, which primarily reflect small vessel cerebrovascular disease, may play a role in the evolution of Alzheimer disease (AD). In a longitudinal study, we investigated whether WMH promote the progression of AD pathology, or alter the association between AD pathology and risk of progression from normal cognition to mild cognitive impairment (MCI).Two sets of analyses were...
Paper Details
Title
White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease
Published Date
Dec 30, 2019
Journal
Volume
94
Issue
9
Pages
e950 - e960
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