225: In-depth characterization of immune cells in preeclampsia using Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)

Preeclampsia is thought to originate in-part due to abnormal maternal immune response to the conceptus. In order to understand the pathogenesis of preeclampsia, a detailed understanding of immune dynamics at the maternal-fetal interface is needed. Recently developed single-cell imaging technology, MIBI-TOF, now enables characterization of immune cell populations at fine detail and in the spatial context of the immune environment. Here, we...