Skeletal muscle transcriptional networks linked to type I myofiber grouping in Parkinson’s disease
Abstract
Parkinson’s disease (PD) is a common neurodegenerative disorder impacting cognition, movement, and quality of life in >10 million individuals worldwide. We recently characterized and quantified a skeletal muscle pathology in PD represented by exaggerated type I myofiber grouping presumed to result from denervation-reinnervation processes. Our previous findings indicated that impaired neuromuscular junction integrity may be involved in type I...
Paper Details
Title
Skeletal muscle transcriptional networks linked to type I myofiber grouping in Parkinson’s disease
Published Date
Feb 1, 2020
Volume
128
Issue
2
Pages
229 - 240
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