‘Off-the-shelf’ allogeneic CAR T cells: development and challenges
Abstract
Autologous chimeric antigen receptor (CAR) T cells have changed the therapeutic landscape in haematological malignancies. Nevertheless, the use of allogeneic CAR T cells from donors has many potential advantages over autologous approaches, such as the immediate availability of cryopreserved batches for patient treatment, possible standardization of the CAR-T cell product, time for multiple cell modifications, redosing or combination of CAR T...
Paper Details
Title
‘Off-the-shelf’ allogeneic CAR T cells: development and challenges
Published Date
Jan 3, 2020
Volume
19
Issue
3
Pages
185 - 199
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