Amelioration of Sepsis-Induced Liver and Lung Injury by a Superoxide Dismutase Mimetic; Role of TNF-α and Caspase-3
Volume: 3, Issue: 1, Pages: 31 - 39
Published: Jan 1, 2020
Abstract
Oxidative stress plays an important role in the development of sepsis and its associated serious consequence leading to multiple organ failure and death. Since the liver and the lungs are among the early affected organs responsible for the mortality in sepsis, we investigated the effect of Tempol, a superoxide dismutase mimetic agent, on lung and liver injuries in a cecal ligation and puncture (CLP)-induced sepsis. Septic animals were given...
Paper Details
Title
Amelioration of Sepsis-Induced Liver and Lung Injury by a Superoxide Dismutase Mimetic; Role of TNF-α and Caspase-3
Published Date
Jan 1, 2020
Volume
3
Issue
1
Pages
31 - 39
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