Insights into the study and origin of the citrullinome in rheumatoid arthritis
Abstract
The presence of autoantibodies and autoreactive T cells to citrullinated proteins and citrullinating enzymes in patients with rheumatoid arthritis (RA), together with the accumulation of citrullinated proteins in rheumatoid joints, provides substantial evidence that dysregulated citrullination is a hallmark feature of RA. However, understanding mechanisms that dysregulate citrullination in RA has important challenges. Citrullination is a normal...
Paper Details
Title
Insights into the study and origin of the citrullinome in rheumatoid arthritis
Published Date
Dec 25, 2019
Journal
Volume
294
Issue
1
Pages
133 - 147
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