Local Vancomycin Concentrations after Intra-articular Injection into the Knee Joint: An Experimental Porcine Study
Abstract
Intra-articular injection of vancomycin may be an important antimicrobial prophylactic supplement to systemic administration in the prevention of prosthetic joint infections. In eight female pigs, 500 mg of diluted vancomycin was given by intra-articular injection into the knee joint. Microdialysis was used for dense sampling of vancomycin concentrations over 12 hours in the synovial fluid of the knee joint, and in the adjacent femoral and...
Paper Details
Title
Local Vancomycin Concentrations after Intra-articular Injection into the Knee Joint: An Experimental Porcine Study
Published Date
Dec 30, 2019
Journal
Volume
34
Issue
09
Pages
936 - 940
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