Platelet thrombus formation in eHUS is prevented by anti-MBL2
Abstract
E. coli associated Hemolytic Uremic Syndrome (epidemic hemolytic uremic syndrome, eHUS) caused by Shiga toxin-producing bacteria is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury that cause acute renal failure in up to 65% of affected patients. We hypothesized that the mannose-binding lectin (MBL) pathway of complement activation plays an important role in human eHUS, as we previously demonstrated...
Paper Details
Title
Platelet thrombus formation in eHUS is prevented by anti-MBL2
Published Date
Dec 27, 2019
Journal
Volume
14
Issue
12
Pages
e0220483 - e0220483
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Notes
History