Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice
Abstract
Cranial irradiation is the main therapeutic treatment for primary and metastatic malignancies in the brain. However, cranial radiation therapy produces long-term impairment in memory, information processing, and attention that contribute to a decline in quality of life. The hippocampal neural network is fundamental for proper storage and retrieval of episodic and spatial memories, suggesting that hippocampal signaling dysfunction could be...
Paper Details
Title
Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice
Published Date
Dec 11, 2019
Journal
Volume
9
Issue
1
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