CRISPR/Cas9 technology: towards a new generation of improved CAR-T cells for anticancer therapies
Abstract
Chimeric antigen receptor (CAR)-modified T cells have raised among other immunotherapies for cancer treatment, being implemented against B-cell malignancies. Despite the promising outcomes of this innovative technology, CAR-T cells are not exempt from limitations that must yet to be overcome in order to provide reliable and more efficient treatments against other types of cancer. The purpose of this review is to shed light on the field of CAR-T...
Paper Details
Title
CRISPR/Cas9 technology: towards a new generation of improved CAR-T cells for anticancer therapies
Published Date
Dec 13, 2019
Volume
19
Issue
3
Pages
191 - 200
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