Microglial activation and tau burden predict cognitive decline in Alzheimer’s Disease
Abstract
null Tau pathology, neuroinflammation, and neurodegeneration are key aspects of Alzheimer’s disease. Understanding whether these features predict cognitive decline, alone or in combination, is crucial to develop new prognostic measures and enhanced stratification for clinical trials. Here, we studied how baseline assessments of in vivo tau pathology (measured by [18F]AV-1451 PET), neuroinflammation (indexed via [11C]PK11195 PET) and brain...
Paper Details
Title
Microglial activation and tau burden predict cognitive decline in Alzheimer’s Disease
Published Date
Nov 8, 2019
Journal
Pages
19011189
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