Anti‑proliferative effect of cardamonin on mTOR inhibitor‑resistant cancer cells

Published: Dec 20, 2019
Abstract
A number of mammalian target of rapamycin (mTOR) inhibitors have been approved for the treatment of certain types of cancer or are currently undergoing clinical trials. However, mTOR targeted therapy exerts selective pressure on tumour cells, which leads to the preferential growth of resistant subpopulations. There are two classes of mTOR inhibitors: i) The rapalogs, such as rapamycin, which bind to the 12‑kDa FK506‑binding...
Paper Details
Title
Anti‑proliferative effect of cardamonin on mTOR inhibitor‑resistant cancer cells
Published Date
Dec 20, 2019
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