Combining epigenetic and immune therapy to overcome cancer resistance

Volume: 65, Pages: 99 - 113
Published: Oct 1, 2020
Abstract
Cancer undergoes “immune editing” to evade destruction by cells of the host immune system including natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). Current adoptive cellular immune therapies include CAR T cells and dendritic cell vaccines, strategies that have yet to show success for a wide range of tumors. Cancer resistance to immune therapy is driven by extrinsic factors and tumor cell intrinsic factors that contribute to immune...
Paper Details
Title
Combining epigenetic and immune therapy to overcome cancer resistance
Published Date
Oct 1, 2020
Volume
65
Pages
99 - 113
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