Metabolite profiling paradoxically reveals favorable levels of lipids, markers of oxidative stress and unsaturated fatty acids in a diabetes susceptible group of Middle Eastern immigrants

Aims The population of immigrants from the Middle East in Sweden show a higher prevalence of type 2 diabetes (T2D) compared to native Swedes. The exact reason for this is unknown. Here, we have performed metabolite profiling to investigate these differences. Methods Metabolite profiling was conducted in Iraqi immigrants ( n = 93) and native Swedes ( n = 77) using two complementary mass spectrometry-based platforms. Differences in metabolite...