The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities
Abstract
Chronic, unresolved tissue inflammation is a well-described feature of obesity, type 2 diabetes mellitus (T2DM) and other insulin-resistant states. In this context, adipose tissue and liver inflammation have been particularly well studied; however, abundant evidence demonstrates that inflammatory processes are also activated in pancreatic islets from obese animals and humans with obesity and/or T2DM. In this Review, we focus on the...
Paper Details
Title
The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities
Published Date
Dec 13, 2019
Journal
Volume
16
Issue
2
Pages
81 - 90
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