Interleukin-22 regulates interferon lambda expression in a mice model of pseudomonas aeruginosa pneumonia
Abstract
Interleukin (IL)-22 is a cytokine involved in tissue protection and repair following lung pathologies. Interferon (IFN)-λ cytokines displayed similar properties during viral infection and a synergy of action between these two players has been documented in the intestine. We hypothesize that during Pseudomonas aeruginosa challenge, IL-22 up-regulates IFN-λ and that IFN-λ exhibits protective functions during Pseudomonas aeruginosa acute pneumonia...
Paper Details
Title
Interleukin-22 regulates interferon lambda expression in a mice model of pseudomonas aeruginosa pneumonia
Published Date
Feb 1, 2020
Journal
Volume
118
Pages
52 - 59
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