PheGWAS: a new dimension to visualize GWAS across multiple phenotypes
Abstract
Motivation PheGWAS was developed to enhance exploration of phenome-wide pleiotropy at the genome-wide level through the efficient generation of a dynamic visualization combining Manhattan plots from GWAS with PheWAS to create a 3D ‘landscape’. Pleiotropy in sub-surface GWAS significance strata can be explored in a sectional view plotted within user defined levels. Further complexity reduction is achieved by confining to a single chromosomal...
Paper Details
Title
PheGWAS: a new dimension to visualize GWAS across multiple phenotypes
Published Date
Dec 20, 2019
Journal
Volume
36
Issue
8
Pages
2500 - 2505
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Notes
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