Analytic and Data Sharing Options in Real‐World Multidatabase Studies of Comparative Effectiveness and Safety of Medical Products

A wide range of analytic and data sharing options are available in nonexperimental multidatabase studies designed to assess the real‐world benefits and risks of medical products. Researchers often consider six scientific domains when choosing among these options—study design, exposure type, outcome type, covariate summarization technique, covariate adjustment method, and data sharing approach. This article reviews available analytic and data...