Dose-related effects of inhaled essential oils on behavioural measures of anxiety and depression and biomarkers of oxidative stress

Essential oils (EOs) are extracts of organic, volatile metabolites of plants that are typically oily liquids at ambient temperatures. Inhalation of EOs can regulate brain health and functions associated with mood and neurodegeneration, reflecting their bioavailability to brain. The aim was to identify physicochemical properties that influenced EO volatility and pathways of brain uptake by inhalation. Dose-dependency of effects, determined as:...