Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells
Abstract
Primary cilia are nonmotile sensory organelles found on the surface of almost all kidney tubule epithelial cells. Being exposed to the tubular lumen, primary cilia are thought to be chemo- and mechanosensors of luminal composition and flux, respectively. We hypothesized that, Na+ transport and primary cilia exist in a sensory functional connection in mature renal tubule epithelial cells. Our results demonstrate that primary cilium length is...
Paper Details
Title
Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells
Published Date
Dec 19, 2019
Journal
Volume
34
Issue
2
Pages
2625 - 2640
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Notes
History