Molecular recognition in the product site of cellobiohydrolase Cel7A regulates processive step length
Abstract
Cellobiohydrolase Cel7A is an industrial important enzyme that breaks down cellulose by a complex processive mechanism. The enzyme threads the reducing end of a cellulose strand into its tunnel-shaped catalytic domain and progresses along the strand while sequentially releasing the disaccharide cellobiose. While some molecular details of this intricate process have emerged, general structure-function relationships for Cel7A remain poorly...
Paper Details
Title
Molecular recognition in the product site of cellobiohydrolase Cel7A regulates processive step length
Published Date
Jan 8, 2020
Journal
Volume
477
Issue
1
Pages
99 - 110
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