Ultrasmall silica nanoparticles directly ligate the T cell receptor complex

Volume: 117, Issue: 1, Pages: 285 - 291
Published: Dec 23, 2019
Abstract
The impact of ultrasmall nanoparticles (<10-nm diameter) on the immune system is poorly understood. Recently, ultrasmall silica nanoparticles (USSN), which have gained increasing attention for therapeutic applications, were shown to stimulate T lymphocytes directly and at relatively low-exposure doses. Delineating underlying mechanisms and associated cell signaling will hasten therapeutic translation and is reported herein. Using competitive...
Paper Details
Title
Ultrasmall silica nanoparticles directly ligate the T cell receptor complex
Published Date
Dec 23, 2019
Volume
117
Issue
1
Pages
285 - 291
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