Perivascular macrophages in the neonatal macaque brain undergo massive necroptosis after simian immunodeficiency virus infection
Abstract
We previously showed that rhesus macaques neonatally infected with simian immunodeficiency virus (SIV) do not develop SIV encephalitis (SIVE) and maintain low brain viral loads despite having similar plasma viral loads compared to SIV-infected adults. We hypothesize that differences in myeloid cell populations that are the known target of SIV and HIV in the brain contribute to the lack of neonatal susceptibility to lentivirus-induced...
Paper Details
Title
Perivascular macrophages in the neonatal macaque brain undergo massive necroptosis after simian immunodeficiency virus infection
Published Date
Dec 26, 2019
Journal
Volume
30
Issue
3
Pages
603 - 613
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