Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease

Volume: 31, Issue: 3, Pages: 205 - 217
Published: Mar 1, 2020
Abstract
Over the past decade, several studies have shown that activity of extra-renal mineralocorticoid receptors (MR) regulates vascular tone, adipogenesis, adipose tissue function, and cardiomyocyte contraction. In mice, abnormal activation of MR in the vasculature and in adipose tissue favors the occurrence of several components of the metabolic syndrome (MetS), such as hypertension, obesity, and glucose intolerance. Accordingly, high levels of...
Paper Details
Title
Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease
Published Date
Mar 1, 2020
Volume
31
Issue
3
Pages
205 - 217
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