Use of β3-methionine as an amino acid substrate of Escherichia coli methionyl-tRNA synthetase

Volume: 209, Issue: 2, Pages: 107435 - 107435
Published: Feb 1, 2020
Abstract
Polypeptides containing β-amino acids are attractive tools for the design of novel proteins having unique properties of medical or industrial interest. Incorporation of β-amino acids in vivo requires the development of efficient aminoacyl-tRNA synthetases specific of these non-canonical amino acids. Here, we have performed a detailed structural and biochemical study of the recognition and use of β3-Met by Escherichia coli methionyl-tRNA...
Paper Details
Title
Use of β3-methionine as an amino acid substrate of Escherichia coli methionyl-tRNA synthetase
Published Date
Feb 1, 2020
Volume
209
Issue
2
Pages
107435 - 107435
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