An NMF-based approach to discover overlooked differentially expressed gene regions from single-cell RNA-seq data
Abstract
Single-cell RNA sequencing has enabled researchers to quantify the transcriptomes of individual cells, infer cell types and investigate differential expression among cell types, which will lead to a better understanding of the regulatory mechanisms of cell states. Transcript diversity caused by phenomena such as aberrant splicing events have been revealed, and differential expression of previously unannotated transcripts might be overlooked by...
Paper Details
Title
An NMF-based approach to discover overlooked differentially expressed gene regions from single-cell RNA-seq data
Published Date
Dec 16, 2019
Volume
2
Issue
1
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