Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling

Volume: 10
Published: Dec 20, 2019
Abstract
The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change their morphology and position within the cells in response to physiological stimuli and these network rearrangements depend on the microtubule (MT) cytoskeleton. Store-operated calcium entry (SOCE) relies on the repositioning of ER tubules to form specific ER-plasma membrane junctions. Indeed,...
Paper Details
Title
Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling
Published Date
Dec 20, 2019
Volume
10
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