Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke

White matter hyperintensity of presumed vascular origin is a risk factor for poor stroke outcomes. In patients with acute ischemic stroke, however, the in vivo mechanisms of white matter microstructural injury are less clear.To characterize the directional diffusivity components in normal-appearing white matter and white matter hyperintensity in acute ischemic stroke patients.A retrospective analysis was performed on a cohort of patients with...