Insulin-Like Growth Factor-1 Is Neuroprotective in Aged Rats With Ischemic Stroke
Abstract
Post-stroke systemic injections of insulin-like growth factor 1 (IGF-1) exert neuroprotective effects in rats. In the current study, we aimed to test the efficacy of IGF-1 neuroprotection in aged rats (24-25 months old) and to compare the results with adult rats (6-7 months old). Furthermore, we addressed putative differences in microglial responses to IGF-1 in adult and aged rats. Rats were subjected to ischemic stroke while they were conscious...
Paper Details
Title
Insulin-Like Growth Factor-1 Is Neuroprotective in Aged Rats With Ischemic Stroke
Published Date
Dec 11, 2019
Volume
11
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