Nucleic acid‐targeted pathogen reduction technique in red blood cells by UV‐generated oxygen radicals for optimising recipient safety

SUMMARY Objectives A novel pathogen reduction technique based on vacuum ultraviolet (VUV) irradiation was developed to reduce pathogen numbers in red blood cell (RBC) components. Background Contaminated blood components pose a great risk of infection in blood recipients. The continuous development of blood screening techniques and pathogen inactivating systems has significantly reduced this risk, but many limitations remain. Methods Escherichia...