A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes

Volume: 107, Issue: 6, Pages: 1383 - 1393
Published: Jan 30, 2020
Abstract
Expression quantitative trait locus (eQTL) studies in human liver are crucial for elucidating how genetic variation influences variability in disease risk and therapeutic outcomes and may help guide strategies to obtain maximal efficacy and safety of clinical interventions. Associations between expression microarray and genome‐wide genotype data from four human liver eQTL studies ( n = 1,183) were analyzed. More than 2.3 million cis ‐eQTLs for...
Paper Details
Title
A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes
Published Date
Jan 30, 2020
Volume
107
Issue
6
Pages
1383 - 1393
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