LogD Contributions of Substituents Commonly Used in Medicinal Chemistry

Volume: 11, Issue: 1, Pages: 72 - 76
Published: Dec 11, 2019
Abstract
The importance of physicochemical property calculation and measurement is well-established in drug discovery. In particular, lipophilicity predictions play a central role in target design and prioritization. While significant progress has been made in our ability to calculate both logP and logD, the quality of these predictions is limited by the size and diversity of the underlying data set. Access to diverse data sets and advanced models is...
Paper Details
Title
LogD Contributions of Substituents Commonly Used in Medicinal Chemistry
Published Date
Dec 11, 2019
Volume
11
Issue
1
Pages
72 - 76
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