miR-214 stimulated by IL-17A regulates bone loss in patients with ankylosing spondylitis
Abstract
Objective Bone loss is common in AS, and miR-214 plays an important role in regulating bone formation. The aim of this study was to investigate the effect of miR-214, the production of which is stimulated by IL-17A, on bone loss in AS. Methods Peripheral blood was obtained from 32 patients with AS and 24 healthy controls. Levels of IL-17A, soluble RANK ligand (RANKL) and osteoprotegerin in serum were evaluated by ELISA, and the relative level of...
Paper Details
Title
miR-214 stimulated by IL-17A regulates bone loss in patients with ankylosing spondylitis
Published Date
Dec 17, 2019
Journal
Volume
59
Issue
5
Pages
1159 - 1169
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