Inosine protects against impairment of memory induced by experimental model of Alzheimer disease: a nucleoside with multitarget brain actions

Inosine is a naturally occurring purine nucleoside formed by adenosine breakdown. This nucleoside is reported to exert potent effects on memory and learning, possibly through its antioxidant and anti-inflammatory actions. The objective is to evaluate the effects of inosine on the behavioral and neurochemical parameters in a rat model of Alzheimer’s disease (AD) induced by streptozotocin (STZ). Adult male rats were divided into four groups:...