Searching for the stimulus controlling brain oxygen supply

The control of cerebral blood flow (CBF) is of great physiological and clinical importance. The brain acts to maintain homeostasis through a very tight balance between CBF and cerebral metabolism of oxygen and glucose, since only very small quantities of these can be stored. The brain adjusts CBF in response to a number of challenges: global changes (blood pressure, blood gas levels) and local changes (neural activity) alongside sympathetic...