Dupilumab as a novel steroid-sparing treatment for IgG4-related disease
Abstract
IgG4-related disease (IgG4-RD) is a rare fibroinflammatory, multisystemic condition with a relapsing-remitting progression.1 The level of serum IgG4 correlates with inflammatory activity and organ involvement.1 Glucocorticoids are first line for IgG4-RD, but there are numerous adverse effects with chronic use.2 Dupilumab is a monoclonal antibody that acts on the interleukin 4 (IL-4) receptor alpha, shared by the IL-4 and IL-13 receptors.1 IL-4...
Paper Details
Title
Dupilumab as a novel steroid-sparing treatment for IgG4-related disease
Published Date
Dec 19, 2019
Volume
79
Issue
4
Pages
549 - 550
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