Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone

Ilka Isfort; Sandra Elges; Magdalene Cyra; Ruth Berthold; Marcus Renner; Gunhild Mechtersheimer; Pierre Åman; Olle Larsson; Nancy Ratner; Susanne Hafner; Wolfgang Hartmann; Marcel Trautmann

doi:https://doi.org/10.1038/s41598-019-56247-8

doi.org/10.1038/s41598-019-56247-8

Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone

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..., Marcel Trautmann

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Scientific Reports4.60

Volume: 9, Issue: 1

Published: Dec 23, 2019

Abstract

Tumors of soft tissue and bone represent a heterogeneous group of neoplasias characterized by a wide variety of genetic aberrations. Albeit knowledge on tumorigenesis in mesenchymal tumors is continuously increasing, specific insights on altered signaling pathways as a basis for molecularly targeted therapeutic strategies are still sparse. The aim of this study was to determine the involvement of YAP1/TAZ-mediated signals in tumors of soft...

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Paper Details

Title

Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone

DOI

doi.org/10.1038/s41598-019-56247-8

Published Date

Dec 23, 2019

Journal

Scientific Reports

Volume

9

Issue

1

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