Original paper
Early neutrophil infiltration is critical for inflammation-sensitized hypoxic-ischemic brain injury in newborns
Volume: 40, Issue: 11, Pages: 2188 - 2200
Published: Dec 16, 2019
Abstract
Neutrophils are the most abundant leukocytes and usually the first immune cell-type recruited to a site of infection or tissue damage. In asphyxiated neonates, elevated peripheral neutrophil counts are associated with poorer neurological outcomes. Induced neutropenia provides brain protection in animal models of neonatal hypoxic-ischemic (HI) injury, but the anti-neutrophil serum used in past studies heavily cross-reacts with monocytes, thus...
Paper Details
Title
Early neutrophil infiltration is critical for inflammation-sensitized hypoxic-ischemic brain injury in newborns
Published Date
Dec 16, 2019
Volume
40
Issue
11
Pages
2188 - 2200
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Notes
History