Gain insight into research trends and influential papers with Research Intelligence.
doi.org/10.1016/j.celrep.2019.11.041

Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation

..., Genhong Cheng
79
Cell Reports8.80
Volume: 29, Issue: 11, Pages: 3551 - 3563.e3
Published: Dec 1, 2019
Abstract
To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence complementation screening to identify potential physical interactions between the HBx protein and 145 IFN-stimulated genes (ISGs). Seven HBx-interacting ISGs have consistent and significant inhibitory effects on HBV replication, among which TRIM5γ suppresses HBV replication...
Paper Fields
Paper Details
Title
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
DOI
doi.org/10.1016/j.celrep.2019.11.041
Published Date
Dec 1, 2019
Journal
Cell Reports
Volume
29
Issue
11
Pages
3551 - 3563.e3
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.