VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in <i>Enterobacterales</i> and Pseudomonas aeruginosa

Jodie Hamrick; Jean Denis Docquier; Tsuyoshi Uehara; Cullen L. Myers; David A. Six; Cassandra L Chatwin; Kaitlyn John; Salvador Vernacchio; Susan M Cusick; Robert E. Lee Trout; Daniel C. Pevear; Denis M. Daigle

doi:https://doi.org/10.1128/aac.01963-19

doi.org/10.1128/aac.01963-19

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

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..., Denis M. Daigle

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Antimicrobial Agents and Chemotherapy4.90

Volume: 64, Issue: 3

Published: Feb 21, 2020

Abstract

As shifts in the epidemiology of β-lactamase-mediated resistance continue, carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa (CRPA) are the most urgent...

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Paper Details

Title

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

DOI

doi.org/10.1128/aac.01963-19

Published Date

Feb 21, 2020

Journal

Antimicrobial Agents and Chemotherapy

Volume

64

Issue

3

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