A clinical decision support tool may help to optimise vedolizumab therapy in Crohn’s disease

Summary Background A clinical decision support tool (CDST) has been validated for predicting treatment effectiveness of vedolizumab (VDZ) in Crohn’s disease. Aim To assess the utility of this CDST for predicting exposure‐efficacy and disease outcomes. Methods Using data from three independent datasets (GEMINI, GETAID and VICTORY), we assessed clinical remission rates and measured VDZ exposure, rapidity of onset of action, response to dose...